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īackground: Seborrheic dermatitis is a common chronic relapsing inflammatory skin disease with unknown etiology. The present study was conducted to determine the relationship between serum selenium. Using zinc and selenium supplements have shown some relieving effects on the symptoms of the disease. Therefore, NBUVB is not likely to improve vitiligo lesions through the increase in serum vitamin D levels.īackground: Seborrheic dermatitis is a common chronic relapsing inflammatory skin disease with unknown etiology. Mean VASI score was 5.45 before the treatment, yet was reduced to 2.24 after treatment, which is a significant change (P<0.001) however, the changes in vitamin D3 levels were not significantly correlated with VASI score (P=0.137).Ĭonclusion: The repigmentation rate in vitiligo lesions are not significantly correlated with serum vitamin D3 levels. Results: Mean serum level of vitamin D3 was 20.78 ng/ml after treatment, which is significantly more compared to the period before the treatment (15.42, P=0.001). Finally, the relationship between the changes in serum vit D3 levels and variations of VASI score was investigated. Further measured were the serum level of 25-hydroxyvitamin D3, VASI score and repigmentation rate before and after the treatment period. Photographs of vitiligo lesions were taken prior to and after completing 60 phototherapy sessions. Methods: Thirty-eight patients with vitiligo were subject to phototherapy with NBUVB. NBUVB appears to be involved in the treatment of vitiligo by increasing the synthesis of vitamin D, which prevents the apoptosis of melanocytes accordingly, we set out to compare the serum level of vitamin D and its variations following NBUVB treatment according to the degree of response to treatment. Narrow band UVB (NBUVB) is a safe and effective treatment for vitiligo that acts by inducing the synthesis of cytokines involved in melanogenesis. īackground: Vitiligo is a pigmentation disorder of the skin characterized by the loss of melanocytes through different mechanisms.
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Background: Vitiligo is a pigmentation disorder of the skin characterized by the loss of melanocytes through different mechanisms.